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Motor Neurone Disease (MND)

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  • 70-year-old patient presented with left-sided weakness and spasticity, and executive dysfunction.
  • Excessive susceptibility artefact in the motor cortex (motor band sign) was most apparent around the right hand motor knob.
  • There was no significant volume loss or corticospinal tract hyperintensity.

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  • A 45-year-old patient had a rapidly progressive tetraparesis over 6 months with upper motor signs and tongue fasiculations.
  • MRI showed subtle hyperintensity within the corticospinal tracts and excessive susceptibility artefact in the motor cortex.

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  • 65-year-old patient presented with twitching arms and legs, muscle weakness and frequent falls.
  • MRI showed marked hyperintensity within the corticospinal tracts and excessive susceptibility artefact in the motor cortex, representing the motor band sign.

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  • 60-year-old patient presenting with brisk reflexes, lower limb weakness and tongue fasiculations.
  • MRI showed mild parietal volume loss near the vertex and marked susceptibility along the motor cortex that extended anteriorly into the paracentral lobule.