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Progressive Supranuclear Palsy (PSP)

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  • 75-year-old patient with postural instability and supranuclear palsy.
  • The midbrain tegmentum is atrophic causing a flattened superior border.
  • The DaTscan shows reduced tracer uptake in the putamina (particularly on the right).

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  • 65-year-old patient presented with instability, free falls, and a vertigcal gaze palsy.
  • MRI showed marked atrophy of the pons.
  • DaTscan showed loss of normal tracer uptake in both corpora striata.

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  • 60-year-old patient presented with poor balance, multiple falls, and rigidity. Initially diagnosed with Parksinson's disease, there was a poor response to levdopa.
  • MRI showed marked midbrian atrophy (as well as a moderate burden of small vessel disease).

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  • 70-year-old patient presented with parkinsonism.
  • MRI showed marked atrophy of the midbrain over a three year period.
  • DaTscan showed high background uptake and with loss of the normal updake in the striatum.